Regulation of Replication-Dependent Histone Biosynthesis by Cell-Cycle Progression / Claire Rose Armstrong.
Histone proteins are essential to genomic function and cellular life. Cells must produce 400 million histone proteins in an approximately 8 hr period within the cell cycle to accommodate duplication of the genome. Under-incorporation of histone proteins into the chromatin leads to genomic instabilit...
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| Format: | Thesis Electronic eBook |
| Language: | English |
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Ann Arbor :
ProQuest Dissertations & Theses,
2022
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