Evolutionary cell biology : the origins of cellular architecture / Michael R. Lynch.

Establishes the foundations of the emerging field of evolutionary cell biology, providing a deep and broad coverage of the literature, with many ideas synthesised and presented for the first time.

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Bibliographic Details
Online Access: Full Text (via ProQuest)
Main Author: Lynch, Michael R. (Author)
Format: Electronic eBook
Language:English
Published: Oxford : Oxford University Press, [2024]
Subjects:

MARC

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050 4 |a QH581.2  |b .L9 2024 
049 |a GWRE 
100 1 |a Lynch, Michael R.,  |e author. 
245 1 0 |a Evolutionary cell biology :  |b the origins of cellular architecture /  |c Michael R. Lynch. 
264 1 |a Oxford :  |b Oxford University Press,  |c [2024] 
264 4 |c ©2024 
300 |a 1 online resource :  |b illustrations. 
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500 |a Also issued in print: 2024. 
504 |a Includes bibliographical references and index. 
520 8 |a Establishes the foundations of the emerging field of evolutionary cell biology, providing a deep and broad coverage of the literature, with many ideas synthesised and presented for the first time. 
521 |a Specialized. 
588 |a Description based on online resource and publisher information; title from PDF title page (viewed on January 30, 2024). 
505 0 |a Cover -- Title page -- Copyright page -- Preface -- Acknowledgment -- Contents -- List of Figures -- List of Tables -- List of Foundations -- Part 1 Introduction -- 1 Evolutionary Cell Biology -- The Dominance of Unicellular Life -- What is Evolutionary Cell Biology? -- The Completeness of Evolutionary Theory -- Evolution Via Nonadaptive Pathways -- The Grand Challenges -- The origin of life -- The roots of organismal complexity -- Molecular stochasticity -- Molecular complexes -- Cellular networks -- Cellular surveillance systems -- Growth regulation -- Biological scaling laws 
505 8 |a 2 The Origin of Cells -- The Earliest Stages -- The alkaline hydrothermal-vent hypothesis -- The terrestrial geothermal-field hypothesis -- An Early RNA World? -- Membranes and the Emergence of Individuality -- Genomic Constraints on the Establishment of Life -- 3 The Major Lines of Descent -- The Primary Domains of Life -- Times of Origin -- The Emergence of Eukaryotes -- The stem eukaryote -- The eukaryotic radiation -- A eukaryotic Big Bang? -- Part 2 The Genetic Mechanisms of Evolution -- 4 The Population-Genetic Environment -- Demystifying Random Genetic Drift 
505 8 |a The Genetic Effective Sizes of Populations -- Probability of Fixation of a Mutant Allele -- Evolution of the Mutation Rate -- High mutability of mutation rates -- Error-prone polymerases -- Optimizing the mutation rate -- The non-random nature of mutation -- Recombination -- Evolution of the recombination rate -- 5 Evolution as a Population-Genetic Process -- The Perils of the Adaptive Paradigm -- The Fitness Effects of New Mutations -- The Classical Model of Sequential Fixation -- Vaulting Barriers to More Complex Adaptations -- Sequential fixation versus stochastic tunnelling 
505 8 |a Two-locus transitions -- More complex scenarios -- Effects of recombination -- The Phylogenetic Dispersion of Mean Phenotypes -- Two-state traits -- Multistate-traits and the drift-barrier hypothesis -- 6 Evolution of Cellular Complexity -- Illusions of Grandeur -- Constructive Neutral Evolution -- Ribosomes -- Evolution by Gene Duplication -- The masking effect -- Neofunctionalization -- Subfunctionalization -- Adaptive-conflict resolution -- The Case for Subfunctionalization -- The Emergence of Modular Gene Subfunctions -- The Passive Origin of Species via Gene Duplication 
505 8 |a Part 3 Basic Cellular Features -- 7 The Cellular Environment -- The Molecular Composition of Cells -- Water -- Elemental composition -- Biomolecules -- Numbers of Biomolecules per Cell -- Passive Transport of Particles through the Cytoplasm -- Intermolecular Encounter Rates -- Temperature-Dependence of Biological Processes -- Energy, Carbon Skeletons, and Cell Yield -- 8 Evolutionary Scaling Relationships in Cell Biology -- Describing Allometric Relationships -- Scaling Laws in Cellular Bioenergetics -- Metabolic rate -- Lifetime energy requirements of a cell 
650 0 |a Cytology. 
650 0 |a Cells  |x Evolution. 
650 7 |a Cell physiology  |2 fast 
650 7 |a Evolution (Biology)  |2 fast 
776 0 8 |i Print version :  |z 9780192847287 
856 4 0 |u http://ebookcentral.proquest.com/lib/ucb/detail.action?docID=31151293  |z Full Text (via ProQuest) 
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952 f f |p Can circulate  |a University of Colorado Boulder  |b Online  |c Online  |d Online  |e QH581.2 .L9 2024  |h Library of Congress classification  |i web