DNA repair protocols : prokaryotic systems / edited by Pat Vaughan.
DNA repair has assumed a new importance with the discovery that malfunctioning of the DNA repair pathways in humans can lead to many disease states. In DNA Repair Protocols: Prokaryotic Systems, well-versed investigators describe in step-by-step detail a wide range of DNA repair activities, from sin...
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| Online Access: |
Full Text (via EBSCO) |
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| Other Authors: | |
| Format: | eBook |
| Language: | English |
| Published: |
Totowa, N.J. :
Humana Press,
©2000.
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| Series: | Methods in molecular biology (Clifton, N.J.) ;
v. 152. |
| Subjects: |
| Summary: | DNA repair has assumed a new importance with the discovery that malfunctioning of the DNA repair pathways in humans can lead to many disease states. In DNA Repair Protocols: Prokaryotic Systems, well-versed investigators describe in step-by-step detail a wide range of DNA repair activities, from single act-alone repair proteins to complex repair systems. These practical protocols not only detail the various repair activities found in cells, but also demonstrate the use of DNA repair proteins and systems as reagents in molecular biology and biotechnology. The techniques described here include mutation and polymorphism detection, which are useful in the search for disease genes and drug response genes, as well as for breeding and trait selection in animals and plants. Each readily reproducible protocol is presented by a hands-on expert in sufficient detail to ensure robust experimental results and is supplemented by chapter introductions, as well as notes offering a wealth of interesting and useful information. Compact and highly practical, DNA Repair Protocols: Prokaryotic Systems provides expert guidance to both the DNA repair researcher studying the fundamental aspects of DNA repair and the applied researcher in human genetics and biotechnology. |
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| Physical Description: | 1 online resource (x, 209 pages) : illustrations |
| Bibliography: | Includes bibliographical references and index. |
| ISBN: | 1592590683 9781592590681 0585354332 9780585354330 089603643X 9780896036437 1280820594 9781280820595 9786610820597 6610820597 |