Practical transfusion medicine / edited by Michael F. Murphy, Derwood H. Pamphilon, Nancy M. Heddle.

The pace of change in transfusion medicine is relentless, with new scientific and technological developments. In addition, efforts are continuing to improve clinical transfusion practice and avoid the use of blood wherever possible. This fourth edition continues to be a concise and comprehensive gui...

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Bibliographic Details
Online Access: Full Text (via ProQuest)
Other Authors: Murphy, Michael F. (Michael Furber) (Editor), Pamphilon, Derwood H. (Editor), Heddle, Nancy M. (Editor)
Format: eBook
Language:English
Published: Chichester, West Sussex, UK : Wiley-Blackwell, a John Wiley & Sons, Ltd. Publication, 2013.
Edition:Fourth edition.
Subjects:
Table of Contents:
  • Introduction: recent evolution of transfusion medicine
  • Part one: basic principles of immunohaematology.
  • Essential immunology for transfusion medicine
  • Human blood group systems
  • Human leucocyte antigens
  • Platelet and neutrophil antigens
  • Part two: Complications of transfusions.
  • Investigation of acute transfusion reactions
  • Haemolytic transfusion reactions
  • Febrile and allergic transfusion reactions
  • Acute lung injury after transfusion
  • Purported adverse effects of transfusion-related immunomodulation and of the transfusion of 'old blood'
  • Transfusion-associated graft-versus-host disease and microchimerism
  • Posttransfusion purpura
  • Transfusion-transmitted infections
  • Bacterial contamination
  • Variant Creutzfeldt-Jakob disease
  • Emerging infections and transfusion safety
  • Part three: Practice in blood centres and hospitals. Regulatory aspects of blood transfusion
  • The role of haemovigilance in transfusion safety
  • Donors and blood collection
  • Blood donation testing and the safety of the blood supply
  • Production and storage of blood components
  • Medicolegal aspects of transfusion practice
  • Blood transfusion in hospitals
  • Blood transfusion in a global context
  • Part four: Clinical transfusion practice. Inherited and acquired coagulation disorders
  • Massive blood loss
  • Good blood management in acute haemorrhage and critical care
  • Haematological disease
  • Blood transfusion in the management of patients with haemoglobinopathies
  • Heparin-induced thrombocytopenia
  • Immunodeficiency and immunoglobulin therapy
  • Fetal, neonatal and childhood transfusions
  • Recombinant proteins in diagnosis and therapy.
  • Part five: Alternatives to transfusion. Principles of patient blood management
  • Autologous transfusion
  • Blood substitutes
  • Pharmacological agents and recombinant activated factor VIIa
  • Part six: Cellular and tissue therapy and organ transplantation. Regulation and accreditation in cellular therapy
  • Stem cell collection and therapeutic apheresis
  • Haemopoietic stem cell processing and storage
  • Haemopoietic stem cell transplantation
  • Cord blood transplantation
  • Recent advances in clinical cellular immunotherapy
  • Tissue banking
  • Part seven: Development of the evidence base for transfusion
  • Observational and interventional trials in transfusion medicine
  • Getting the most out of the evidence for transfusion medicine
  • Variation in transfusion practice and how to influence clinicians' use of blood in hospitals
  • Scanning the future of transfusion medicine.