Renal medullary circulation / Louise C. Evans and Allen W. Cowley Jr.

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Bibliographic Details
Online Access: Full Text (via Colloquium Digital Library)
Main Authors: Evans, Louise C. (Author), Cowley, Allen W., Jr (Author)
Format: eBook
Language:English
Published: San Rafael, California (1537 Fourth Street, San Rafael, CA 94901 USA) : Morgan & Claypool, 2015.
Series:Colloquium series on integrated systems physiology ; #64.
Subjects:
Table of Contents:
  • 1. Introduction
  • 2. Anatomy and ultrastructure
  • 2.1 Vascular structures within the renal medulla
  • 2.2 Structural organization of the outer medulla
  • 2.3 Structural organization of the inner medulla
  • 3. Functional roles of medullary blood flow
  • 3.1 Countercurrent multiplication
  • 3.2 Countercurrent exchange
  • 3.3 Pressure natriuresis
  • 3.4 Medullary blood flow and tissue oxygenation
  • 3.5 Mathematical modeling of medullary function from medullary structure
  • 4. Experimental assessment of medullary perfusion
  • 4.1 Video microscopy
  • 4.2 Measurement of medullary blood flow using laser-Doppler flowmetry
  • 4.3 Ultrasound as a tool to assess medullary perfusion
  • 4.4 Measurement of tissue oxygenation
  • 4.5 Infusion of vasoactive compounds into the renal medulla
  • 4.6 In vitro microperfusion of isolated microvessels
  • 5. Pericytes and non-hormonal regulation of vasa recta tone
  • 5.1 Pericytes
  • 5.2 Mechanosensitive responses
  • 5.3 Renal innervation
  • 6. Hormonal regulation of vasa recta tone
  • 6.1 Vasopressin
  • 6.2 Angiotensin
  • 6.3 Nitric oxide
  • 6.4 Reactive oxygen species
  • 6.5 Endothelin
  • 6.6 Adrenomedullin
  • 6.7 Adenosine
  • 6.8 Arachadonic acid metabolites
  • 6.9 Kinins
  • 7. Reductions in medullary blood flow initiate hypertension
  • 8. The Dahl salt-sensitive rat as a model of reduced medullary blood flow
  • 9. Summary
  • References
  • Author biographies.