Inorganic polyphosphates in Eukaryotic cells / Tatiana Kulakovskaya, Evgeny Pavlov, Elena N. Dedkova, editors.
The book elucidates the role of inorganic polyphosphates in eukaryotic cells, from fungi and protozoa to human being. To date, there is plenty of evidence that these anionic biopolymers occurring in the cells of all living organisms, from bacteria to humans, perform numerous regulatory functions. Th...
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Cham, Switzerland :
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2016.
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| 245 | 0 | 0 | |a Inorganic polyphosphates in Eukaryotic cells / |c Tatiana Kulakovskaya, Evgeny Pavlov, Elena N. Dedkova, editors. |
| 260 | |a Cham, Switzerland : |b Springer, |c 2016. | ||
| 300 | |a 1 online resource. | ||
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| 505 | 0 | |a Preface; Contents; Part I: Lower Eukaryotes; 1: The Role of Inorganic Polyphosphates in Stress Response and Regulation of Enzyme Activities in Yeast; 1.1 Introduction; 1.2 Pi Limitation and Excess; 1.3 Nitrogen Starvation; 1.4 Toxic Effects of Manganese; 1.5 Adaptation to Hydrophobic Carbon Sources; 1.6 PolyP and Regulation of Enzyme Activities; References; 2: Yeast Polyphosphatases PPX1 and PPN1: Properties, Functions, and Localization; 2.1 Introduction; 2.2 Structural Features; 2.3 Substrate Specificity, Kinetics, Inhibitors and Activators; 2.4 Cellular Localization. | |
| 505 | 8 | |a 2.5 Interplay of PPX1 and PPN1; 2.6 Cellular PolyP Under PPX1 and PPN1 Knockout; 2.7 Cellular PolyP Under PPX1 and PPN1 Overexpression; 2.8 Orthologous Proteins in Other Organisms; References; 3: Polyphosphate Storage and Function in Acidocalcisomes; 3.1 Introduction; 3.2 Polyphosphate Content of Acidocalcisomes; 3.3 Synthesis and Degradation of Acidocalcisome PolyP; 3.4 Functions of Acidocalcisome PolyP; References; 4: Inorganic Polyphosphates in Mycorrhiza; 4.1 Mycorrhizal Symbiosis; 4.2 Identification of Polyphosphate in Mycorrhizal Fungi. | |
| 505 | 8 | |a 4.3 Technical Breakthroughs for Specific Detection of Polyphosphate; 4.4 Dynamics of Polyphosphate in Mycorrhizal Fungi; 4.5 Cellular Processes of Polyphosphate Accumulation; 4.6 Perspectives; References; 5: Functions of Inositol Polyphosphate and Inorganic Polyphosphate in Yeast and Amoeba; 5.1 Introduction; 5.2 Introduction to Inositol Polyphosphates; 5.3 Inositol Pyrophosphate Metabolism and Functions; 5.4 Inorganic Polyphosphate Eukaryote Metabolism; 5.5 Inositol Pyrophosphate and Inorganic Polyphosphate Metabolic Connected. | |
| 505 | 8 | |a 5.6 Inorganic Polyphosphate Function in Saccharomyces cerevisiae; 5.7 Inorganic Polyphosphate Function in Dictyostelium discoideum; 5.8 Protein Polyphosphorylation; 5.9 Concluding Remarks; References; Part II: Higher Eukaryotes; 6: Methods of Inorganic Polyphosphate (PolyP) Assay in Higher Eukaryotic Cells; 6.1 Introduction; 6.2 Overview of the Experimental Approaches for Investigation of PolyP; 6.3 Extraction and Quantification of PolyP in Eukaryotic Cells and Tissues; 6.4 Sizing of the Extracted PolyP; 6.5 Extraction and Assessment of the Complexed PolyP. | |
| 505 | 8 | |a 6.6 Visualisation and Assessment of PolyP in Living Cells; 6.7 Future Methods Development; References; 7: Inorganic Polyphosphates in the Mitochondria of Mammalian Cells; 7.1 Introduction; 7.2 From Industry and Agriculture to Medicine: Sources of PolyPs in Mammalian Cells; 7.3 Pathways for PolyP Synthesis and Degradation; 7.4 Mitochondrial Metabolism of PolyP in Mammalian Cells; 7.5 Effects of PolyP Depletion on the Respiratory Chain Activity; 7.6 Role of the Inorganic PolyP in Mitochondrial Ca2+ Uptake and Ca2+ Buffering. | |
| 504 | |a Includes bibliographical references at the end of each chapters. | ||
| 520 | |a The book elucidates the role of inorganic polyphosphates in eukaryotic cells, from fungi and protozoa to human being. To date, there is plenty of evidence that these anionic biopolymers occurring in the cells of all living organisms, from bacteria to humans, perform numerous regulatory functions. The book describes the evolution of PolyPs, their role in lower eukaryotes and their involvement in various processes in the human organism, as well as its use in biomaterials such as bioactive glass and engineered bone tissue. The aim of this book is to summarize the data of the past decade on the functional role of inorganic polyphosphates in eukaryotes and discuss their biological role also in context of common human diseases. The book will provide a modern concept of the functional significance of these biopolymers, useful for researchers in cell biology, biochemistry, molecular biology and biomedicine alike. | ||
| 650 | 0 | |a Eukaryotic cells. | |
| 650 | 0 | |a Inorganic polyphosphates. | |
| 650 | 7 | |a Eukaryotic cells. |2 fast |0 (OCoLC)fst00916456. | |
| 650 | 7 | |a Inorganic polyphosphates. |2 fast |0 (OCoLC)fst01920565. | |
| 700 | 1 | |a Kulakovskai︠a︡, T. V. |q (Tatʹi︠a︡na Valentinovna), |e editor. | |
| 700 | 1 | |a Pavlov, Evgeny, |e editor. | |
| 700 | 1 | |a Dedkova, Elena N., |e editor. | |
| 776 | 0 | 8 | |i Print version: |t Inorganic polyphosphates in Eukaryotic cells. |d Cham, Switzerland : Springer, 2016 |z 9783319410715 |z 3319410717 |w (OCoLC)950953427. |
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