Early vascular aging (EVA) : new directions in cardiovascular protection / edited by Peter M. Nilsson, MD, PhD, Michael H. Olson, MD, PhD, Stéphane Laurent, MD, PhD.
Early Vascular Aging (EVA): New Directions in Cardiovascular Protection brings together the last decade of research related to the characterization of EVA, as well as the predictive power of pulse wave velocity (PWV). The book presents a novel approach to the problem of cardiovascular disease, showi...
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Full Text (via ScienceDirect) |
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| Format: | eBook |
| Language: | English |
| Published: |
London :
Elsevier,
[2015]
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| Subjects: |
Table of Contents:
- Front Cover; Early Vascular Aging (EVA); Copyright Page; Contents; List of Contributors; Preface; 1 Historical Aspects and Biology of Aging; Evolutionary Traits, Genes, and the Environment Influencing Aging; Changes During the Twentieth Century in Life Expectancy; Early Life Programming Effects; Vascular Aging in Perspective; New Models and Interventions to Influence Aging; Acknowledgment; References; 2 Cellular and Molecular Determinants of Arterial Aging; Introduction; Cytoskeletal and Contractile Proteins in the Aging Arterial Wall; Cytoskeletal Proteins; Contractile Proteins.
- ConclusionAcknowledgment; References; 3 Aging Population: Challenges and Opportunities in a Life Course Perspective; Aging Populations-Between Decreasing Mortality and Improved Health; Living Longer, but with More Chronic Diseases; From Healthcare of Older Subjects to Life Course Approach; Strategies for Healthy Aging; References; 4 Population-Based Studies: Milestones on the Epidemiological Timeline; Introduction; Proven Prognostic Power in High-Risk Subpopulations; Proven Prognostic Power in the General Population; Beyond Curve Divergence; Data Harmonization.
- Quo Vadis: More Depth and Breadth of Phenotyping, More Comprehensive Populations, Longer Event HorizonsMore Depth and Breadth of Phenotyping: Wave Reflection; More Depth and Breadth of Phenotyping: Time-Varying Phenomena; More Comprehensive Populations: Studying the Early Impact of Cardiovascular Risk Factors; More Comprehensive Populations: Early Vascular Aging and Stroke-Prone Populations; Longer Event Horizons; References; 5 Lessons from the Amsterdam Growth and Health Longitudinal Study; AGAHLS-The Cohort Profile; Study Design and Population.
- The Introduction of Large Artery Properties Measures-Rationale and MethodsDefinition of Vascular Aging Phenotypes; Early Determinants of Arterial Stiffness-A Life Course Approach; Cumulative Burden and Trajectories of Biological RFs-The Critical Role of BP and (Central) Fatness; Blood Pressure; Total and Central Fatness; Blood Lipids and Physical Fitness; Cumulative Burden and Trajectories of Lifestyle RFs-The Preventive Role of Lifelong Lifestyles; Dietary Intake; Habitual Physical Activity; Sedentary Behavior; Additional Studies; Conclusions; Acknowledgment; References.