Protein-protein interactions as new drug targets [electronic resource] / Enno Klussmann, John Scott, editors ; contributors, E.M. Aandahl [and others]
Disease-relevant intracellular protein-protein interactions occurring at defined cellular sites possess great potential as drug targets. They permit highly specific pharmacological interference with defined cellular functions. Drugs targeting such interactions are likely to act with fewer side effec...
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| Online Access: |
Full Text (via Springer) |
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| Other Authors: | , , |
| Format: | Electronic eBook |
| Language: | English |
| Published: |
Berlin :
Springer,
©2008.
|
| Series: | Handbook of experimental pharmacology ;
v. 186. |
| Subjects: |
| Summary: | Disease-relevant intracellular protein-protein interactions occurring at defined cellular sites possess great potential as drug targets. They permit highly specific pharmacological interference with defined cellular functions. Drugs targeting such interactions are likely to act with fewer side effects than conventional medication influencing whole cell functions. This book discusses therapeutically relevant protein-protein interactions with a major focus on scaffolding proteins tethering signal transduction processes to defined cellular compartments by direct protein-protein interactions. Recent advances in the development of pharmacological agents interfering with protein-protein interactions are highlighted. |
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| Physical Description: | 1 online resource (xv, 512 pages) : illustrations. |
| Bibliography: | Includes bibliographical references and index. |
| ISBN: | 9783540728436 3540728430 9783540728429 3540728422 |
| ISSN: | 0171-2004 ; |