The in-vivo inactivation of Factor VIII (antihemophilic globulin) by hydrazine : Its relation to fibrinolytic mechanism / Jarrell D. Bairrington.
The in-vivo effects of a 0.6 LD/50 dose of hydrazine on the prothrombin activating mechanism and the fibrinolytic mechanism were studied in ether anesthetized rats.
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| Format: | Government Document Book |
| Language: | English |
| Published: |
Brooks Air Force Base, Texas :
USAF School of Aerospace Medicine, Aerospace Medical Division (AFSC),
1967.
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| Series: | SAM-TR ;
66-201. |
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| Summary: | The in-vivo effects of a 0.6 LD/50 dose of hydrazine on the prothrombin activating mechanism and the fibrinolytic mechanism were studied in ether anesthetized rats. Decrease of Factor VIII activity was correlated with activation of fibrinolysis due to decrease of the euglobulin inhibitor. The possible usefulness of these findings for a diagnostic test for hydrazine intoxication in workers with propellants and the mechanism of the decrease of Factor VIII and euglobulin inhibitor are discussed. |
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| Item Description: | "January 1967." Also as: Aerospace Medicine, Volume 38, Number 1, (1967), pp. 5-9. |
| Physical Description: | 5 pages : illustrations ; 27 cm. |
| Bibliography: | Includes bibliographical references. |