|
|
|
|
| LEADER |
00000cam a2200000Ii 4500 |
| 001 |
b8443530 |
| 003 |
CoU |
| 005 |
20151204092632.0 |
| 008 |
130911s2015 enka b 001 0 eng d |
| 020 |
|
|
|a 9781849739085
|
| 020 |
|
|
|a 1849739080
|
| 020 |
|
|
|z 9781782620938 (PDF eISBN)
|
| 035 |
|
|
|a (OCoLC)ocn919488397
|
| 035 |
|
|
|a (OCoLC)919488397
|z (OCoLC)918999967
|
| 040 |
|
|
|a EQO
|b eng
|e rda
|c EQO
|d OCLCO
|d UZ0
|d YDXCP
|d OCLCF
|d NLE
|d BDX
|d CUD
|
| 049 |
|
|
|a CODA
|
| 050 |
1 |
4 |
|a RM301.25
|b .F732 2015
|
| 245 |
0 |
0 |
|a Fragment-based drug discovery /
|c edited by Steven Howard, Chris Abell.
|
| 264 |
|
1 |
|a Cambridge :
|b Royal Society of Chemistry,
|c [2015]
|
| 300 |
|
|
|a xlix, 264 pages :
|b illustrations (some colour) ;
|c 25 cm.
|
| 336 |
|
|
|a text
|b txt
|2 rdacontent.
|
| 337 |
|
|
|a unmediated
|b n
|2 rdamedia.
|
| 338 |
|
|
|a volume
|b nc
|2 rdacarrier.
|
| 490 |
1 |
|
|a RSC drug discovery series ;
|v 47.
|
| 504 |
|
|
|a Includes bibliographical references and index.
|
| 505 |
0 |
|
|a ch. 1 Different Flavours of Fragments / Claudio Dagostin -- 1.1.Fragment-Based Drug Discovery -- 1.2.Different Types of Fragments -- 1.3.How We Identify Fragments -- 1.4.Selectivity -- 1.5.Applications of Fragment-Based Methods -- 1.5.1.Assigning Function -- 1.5.2.Assessing Ligandability -- 1.5.3.Speeding Up Chemical Validation -- 1.6.Targeting Protein -- Protein Interactions and Beyond -- 1.7.Targeting Oligonucleotides -- 1.8.Concluding Remarks -- References -- ch. 2 Getting the Most Value from Your Screens: Advances in Hardware, Software, and Methodologies to Enhance Surface Plasmon Resonance Based Fragment Screening and Hit-to-Lead Support / Brandon J. Bravo -- 2.1.Introduction -- 2.2.SPR Technology as Applied to FBS -- 2.3.The Basic Screening Cascade -- 2.4.Advances in Data Reduction and Active Selection in Primary Screening -- 2.4.1.Robust Drift Correction by Local Estimation -- 2.4.2.Method #1 for Hit Detection: Box Plots --
|
| 650 |
|
0 |
|a Drug development.
|0 http://id.loc.gov/authorities/subjects/sh97007921.
|
| 650 |
|
0 |
|a Ligands (Biochemistry)
|0 http://id.loc.gov/authorities/subjects/sh89002279.
|
| 650 |
|
7 |
|a Drug development.
|2 fast
|0 (OCoLC)fst00898670.
|
| 650 |
|
7 |
|a Ligands (Biochemistry)
|2 fast
|0 (OCoLC)fst00998471.
|
| 700 |
1 |
|
|a Howard, Steven,
|c PhD,
|e editor.
|0 http://id.loc.gov/authorities/names/nb2015015571.
|
| 700 |
1 |
|
|a Abell, C.,
|e editor.
|0 http://id.loc.gov/authorities/names/n85146971
|1 http://isni.org/isni/0000000116260147.
|
| 710 |
2 |
|
|a Royal Society of Chemistry (Great Britain),
|e publisher.
|0 http://id.loc.gov/authorities/names/n81122723
|1 http://isni.org/isni/0000000120973756.
|
| 830 |
|
0 |
|a RSC drug discovery series ;
|v 47.
|0 http://id.loc.gov/authorities/names/no2010092643.
|
| 907 |
|
|
|a .b84435306
|b 03-19-20
|c 10-21-15
|
| 998 |
|
|
|a sci
|b 12-04-15
|c a
|d m
|e -
|f eng
|g enk
|h 0
|i 1
|
| 907 |
|
|
|a .b84435306
|b 07-23-17
|c 10-21-15
|
| 944 |
|
|
|a MARS - RDA ENRICHED
|
| 907 |
|
|
|a .b84435306
|b 01-04-16
|c 10-21-15
|
| 907 |
|
|
|a .b84435306
|b 12-04-15
|c 10-21-15
|
| 946 |
|
|
|a hl
|
| 999 |
f |
f |
|i 3b7dc868-415e-58aa-bb98-4f42dc0b48ca
|s 65ccec12-4ee8-52bc-80e2-15d5df51935c
|
| 952 |
f |
f |
|p Can circulate
|a University of Colorado Boulder
|b Boulder Campus
|c Norlin
|d Norlin Library - Science Stacks
|e RM301.25 .F732 2015
|h Library of Congress classification
|i book
|m U183070012328
|n 1
|
