Surface-enhanced raman medical probes and system for disease diagnosis and drug testing [electronic resource]
A probe for a surface-enhanced Raman scattering spectrometer includes a member of optically transmissive material for receiving the excitation radiation from a laser and for carrying the radiation emitted from a specimen to a detector. An end of the member for placing against the specimen has a coat...
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Online Access |
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| Format: | Government Document Electronic eBook |
| Language: | English |
| Published: |
Oak Ridge, Tenn. : Oak Ridge, Tenn. :
Lockheed Martin Energy Research Corp. ; distributed by the Office of Scientific and Technical Information, U.S. Department of Energy,
1999.
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| Summary: | A probe for a surface-enhanced Raman scattering spectrometer includes a member of optically transmissive material for receiving the excitation radiation from a laser and for carrying the radiation emitted from a specimen to a detector. An end of the member for placing against the specimen has a coating that produces surface enhancement of the specimen during Raman scattering spectroscopic analysis. Specifically the coating is formed by a first layer of microparticles on the member and a metal layer over the first layer. The first layer may form a microstructure surface over which a metal layer is applied. Alternatively the coating may be a material containing microparticles of a metal. An optional layer of a material may be applied to the metal layer to concentrate onto the probe compounds of analytical interest onto the probe. Surface-Enhanced; Raman; Medical; Probes; Disease; Diagnosis; Drug; Testing; Probe; Surface-Enhanced; Raman; Scattering; Spectrometer; Optically; Transmissive; Material; Receiving; Excitation; Radiation; Laser; Carrying; Radiation; Emitted; Specimen; Detector; Placing; Specimen; Coating; Produces; Surface; Enhancement; Specimen; Raman; Scattering; Spectroscopic; Analysis; Specifically; Coating; Formed; Layer; Microparticles; Metal; Layer; Layer; Layer; Form; Microstructure; Surface; Metal; Layer; Applied; Alternatively; Coating; Material; Containing; Microparticles; Metal; Optional; Layer; Material; Applied; Metal; Layer; Concentrate; Probe; Compounds; Analytical; Probe; Excitation Radiation; Surface-Enhanced Raman; Surface-Enhanced Raman; Spectroscopic Analysis; Raman Scattering; Raman Scattering; Metal Layer; Metal Layer; Metal Layer; Material Containing; Radiation Emitted; Enhanced Raman; Enhanced Raman; Scattering Spectrometer; Transmissive Material. |
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| Item Description: | Published through SciTech Connect. 01/01/1999. "us 5864397" Vo-Dinh, Tuan. |