The science of reconstructive transplantation / Gerald Brandacher, editor.
This volume presents a comprehensive overview of the latest advances in basic and translational research in the field of reconstructive transplantation and its potential therapeutic implications. Dr. Thomas E. Starzl and Dr. Raimund Margreiter, both pioneers in the field of transplantation, have wri...
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Full Text (via Springer) |
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| Format: | eBook |
| Language: | English |
| Published: |
New York :
Humana Press,
2015.
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| Series: | Stem cell biology and regenerative medicine.
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| Subjects: |
MARC
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| 245 | 0 | 4 | |a The science of reconstructive transplantation / |c Gerald Brandacher, editor. |
| 264 | 1 | |a New York : |b Humana Press, |c 2015. | |
| 300 | |a 1 online resource : |b color illustrations. | ||
| 336 | |a text |b txt |2 rdacontent. | ||
| 337 | |a computer |b c |2 rdamedia. | ||
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| 490 | 1 | |a Stem cell biology and regenerative medicine, |x 2196-8993. | |
| 504 | |a Includes bibliographical references and index. | ||
| 505 | 0 | |a Foreword: The Science of ReconstructiveTransplantation; Foreword: The Science of Reconstructive Transplantation; Preface; Contents; Contributors; Part I ; Introduction, History, and Clinical Impact; Chapter-1; Reconstructive Transplantation: From Scientific Dream to Clinical Reality; Introduction; Transplantation in Antiquity; A Renaissance in Transplantation: The Nineteenth Century; Transplantation Immunology in the Twentieth Century: The Key to Success; History and Current Status of Reconstructive Transplantation; Outlook; References; Chapter-2. | |
| 505 | 8 | |a Clinical Pearls and Pitfalls in Reconstructive TransplantationIndications/Contraindications; Technique; Preoperative Planning for the Operation; Preparation of the Recipient; Harvest and Preparation of the Donor Graft; Surgical Dissection of the Recipient; Preparation of the Donor Graft; Bone Fixation; Restoration of Blood flow; Nerve Repair; Tendon Repair; Venous Repair and Outflow; Skin Closure; Early Postoperative Care; Discussion; References; Chapter-3; Reconstructive Transplantation: What Can We Learn from Solid Organ Transplantation?; Patient and Center Selection; Donor Selection. | |
| 505 | 8 | |a Allograft Procurement and PreservationOrgan Sharing and Allocation; Immunosuppression; Rejection; Complications of Immunosuppression; Conclusions; References; Chapter-4; The Daily Life of a Hand Transplant Recipient; References; Part II ; Specific Areas of Research; Chapter-5; Small Animal Models for Reconstructive Transplantation; Introduction; Animal Models for Transplantation Research; Rat Hind Limb Transplant Models; Mouse Models; Face Transplant Models; Discussion; References; Chapter-6; Use of Large-Animal and Nonhuman Primate Models for Reconstructive Transplantation; Introduction. | |
| 505 | 8 | |a Small-Animal Models and Mixed ChimerismCo-Stimulatory Blockade in Rodents; Large-Animal Models; Common Large-Animal Models; Canine Models in VCA; Swine Models in VCA; Nonhuman Primates; Conclusions; References; Chapter-7; Unique Immunological Features of Vascularized Composite Allografts; Introduction; History; Components of Vascularized Composite Allografts; Reasons for High Immunogenicity of Skin; Immune Activation; Role of Adhesion Molecules; Adhesion Molecules in VCA; Rejection in VCA; Immunohistochemical Studies of Rejection in VCA; Humoral Immunity in VCA; Regulatory T Cells. | |
| 505 | 8 | |a Vascularized Bone Marrow TransplantConundrum of Chronic Rejection in VCA; Conclusions; References; Chapter-8; Immunological Similarities and Differences Between Extremity and Face Transplants; Introduction; Acute Rejection; Chronic Rejection; Graft-Versus-Host Disease, Chimerism, and Tolerance; Immunosuppression and Complications; Conclusions; References; Chapter-9; Advances in Diagnosing Skin Rejection and Immune Monitoring; Skin Rejection; Introduction; Immunology of Skin Rejection; Cell Mediators of Skin Rejection; Lymphocyte Migration to the Skin. | |
| 520 | |a This volume presents a comprehensive overview of the latest advances in basic and translational research in the field of reconstructive transplantation and its potential therapeutic implications. Dr. Thomas E. Starzl and Dr. Raimund Margreiter, both pioneers in the field of transplantation, have written forewords for the book. The volume spans such topics as skin rejection, immune monitoring, stem cell-based immunomodulatory strategies, costimulatory blockade, tolerance induction, chronic rejection, ischemia reperfusion injury, nerve regeneration, cortical reintegration, and small and large animal models for reconstructive transplantation. The book is intended for biomedical researchers and basic scientists in the field of reconstructive transplantation, transplant immunology and regenerative medicine, as well as clinicians, surgeons and multidisciplinary specialists, who are practicing or interested in this novel and exciting field. Postgraduate fellows and students will also find it a valuable reference. | ||
| 588 | 0 | |a Online resource; title from PDF title page (EBSCO, viewed May 18, 2015) | |
| 650 | 0 | |a Transplantation of organs, tissues, etc. |0 http://id.loc.gov/authorities/subjects/sh85137008. | |
| 650 | 7 | |a Transplantation of organs, tissues, etc. |2 fast |0 (OCoLC)fst01154919. | |
| 700 | 1 | |a Brandacher, Gerald, |e editor. |0 http://id.loc.gov/authorities/names/nb2011032782 |1 http://isni.org/isni/0000000360372415. | |
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