Total synthesis of thielocin B1 as a protein-protein interaction inhibitor of PAC3 homodimer / Kosuke Ohsawa.
This book focuses on thielocin B1 (TB1), which was found to be an inhibitor of protein?protein interactions (PPIs) of proteasome assembling chaperone (PAC) 3 homodimer, and elucidates the mechanism by nuclear magnetic resonance (NMR) studies. Interfaces of PPIs recently have been expected to be nove...
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Full Text (via Springer) |
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| Format: | eBook |
| Language: | English |
| Published: |
Tokyo :
Springer,
2015.
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| Series: | Springer theses.
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Table of Contents:
- Introduction
- Total Synthesis of Thielocin B1 and NMR Chemical Shift Perturbation Experiments with PAC3 Homodimer
- Synthesis of Spin-labeled Thielocin B1 and Observation of Paramagnetic Relaxation Enhancement Effects
- An Improved Method for the Direct Formylation ob Substituted Benzenes Using Dichloromethyl Methyl Ether-Silver Trifluoromethanesulfonate
- Conclusions.