Biochemical roles of eukaryotic cell surface macromolecules / Abhijit Chakrabarti.

Consists of critical reviews and original research papers from the 2014 International Symposium on the "Biochemical Role of Eukaryotic Cell Surface Macromolecules". Topics covered include: · neurochemical and biochemical analysis of cell surface glycoconjugates · membrane skeletal organiza...

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Bibliographic Details
Online Access: Full Text (via Springer)
Main Author: Chakrabarti, Abhijit (Author)
Format: eBook
Language:English
Published: Cham, Switzerland : Springer, 2015.
Series:Advances in experimental medicine and biology ; 842.
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245 1 0 |a Biochemical roles of eukaryotic cell surface macromolecules /  |c Abhijit Chakrabarti. 
264 1 |a Cham, Switzerland :  |b Springer,  |c 2015. 
264 4 |c ©2015. 
300 |a 1 online resource (407 pages) :  |b illustrations (some color), tables. 
336 |a text  |b txt  |2 rdacontent. 
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490 1 |a Advances in Experimental Medicine and Biology,  |x 2214-8019 ;  |v Volume 842. 
504 |a Includes bibliographical references and index. 
505 0 |6 880-01  |a Preface; Contents; Chapter 1: Human-Specific Evolutionary Changes in the Biology of Siglecs; Introduction; Human-Specific Changes in Siglecs; Siglec-1/Sialoadhesin; Siglec-3/CD33; Siglec-5 and -14; Siglec-6; Siglec-9; Siglec-11 and -16; Siglec-XII; Siglec-13; Siglec-17; Conclusions and Perspectives; References; Chapter 2: Structural Changes of GPI Anchor After Its Attachment to Proteins: Functional Significance; Introduction; Biosynthesis of GPI and Its Attachment to Proteins; GPI Remodeling Reactions That Occur After Attachment to Proteins; Inositol-Deacylation by PGAP1 in the ER. 
505 8 |a Removal of an EtNP Side Branch from the Second Mannose by PGAP5 in the ER Fatty Acid Remodeling of GPI-AP in the Golgi; Biological Significance of Fatty Acid Remodeling; References; Chapter 3: Novel Insights in Membrane Biology Utilizing Fluorescence Recovery After Photobleaching; The Dynamic Membrane; Fluorescence Recovery After Photobleaching; Lipid Dynamics by FRAP; GPCR Activation: Manifestations in Receptor Dynamics; Dynamic Confinement of GPCRs Upon Cholesterol Depletion: Insight from Bleach Area-Dependent FRAP; Are Signaling and Dynamics Correlated? 
505 8 |a Lateral Dynamics as Readout of Infection Conclusion and Future Perspectives; References; Chapter 4: Defects in Erythrocyte Membrane Skeletal Architecture; Introduction; Membrane Skeleton; Erythroid Membrane Skeleton; Lipid Bilayer: Membrane Skeleton Interactions; Assembly of the Membrane-Skeleton of Erythroid Cells; Defects in Membrane Skeleton; Hereditary Spherocytosis; Molecular Defects in HS; Pathophysiology; Laboratory Features and Treatment; Hereditary Elliptocytosis; Molecular Defects in HE; Laboratory Features and Treatment; Malaria and the Erythrocyte Membrane Skeleton Alterations. 
505 8 |a ConclusionReferences; Chapter 5: Membrane Rafts in the Erythrocyte Membrane: A Novel Role of MPP1p55; Introduction; Erythrocyte Membrane Rafts; Stomatin, Flotillins and MPP1 Are the Stable Components of Erythrocyte Rafts; Stomatin; Flotillins; MPP1; Visualization of Erythrocyte Membrane Rafts; Role of Erythrocyte Membrane Rafts in Signaling; Erythrocyte Rafts and Pathology; MPP1 and Its Palmitoylation Play a Crucial Role in Lateral Membrane Organization in Erythroid Cells; The Involvement of Actin in Erythrocyte Membrane Rafts Organization?; Conclusions; References. 
520 |a Consists of critical reviews and original research papers from the 2014 International Symposium on the "Biochemical Role of Eukaryotic Cell Surface Macromolecules". Topics covered include: · neurochemical and biochemical analysis of cell surface glycoconjugates · membrane skeletal organization · GPCRs and other receptors · biophysical approaches to study membrane interactions · glycoconjugate metabolism · dysregulation · molecular mechanisms involved in cell-cell and cell-matrix interaction · glycans in infectious and neurological diseases · cancer and glycosyltransferases as drug targets. 
588 0 |a Print version record. 
650 0 |a Eukaryotic cells. 
650 0 |a Molecular biology. 
650 0 |a Cell receptors. 
650 7 |a Cell receptors.  |2 fast  |0 (OCoLC)fst00850227. 
650 7 |a Eukaryotic cells.  |2 fast  |0 (OCoLC)fst00916456. 
650 7 |a Molecular biology.  |2 fast  |0 (OCoLC)fst01024734. 
776 0 8 |i Print version:  |a Chakrabarti, Abhijit.  |t Biochemical roles of eukaryotic cell surface macromolecules.  |d Cham, Switzerland : Springer, ©2015  |h ix, 411 pages  |k Advances in experimental medicine and biology ; Volume 842  |x 2214-8019  |z 9783319112794  |w (DLC) 2014955053. 
830 0 |a Advances in experimental medicine and biology ;  |v 842. 
856 4 0 |u https://colorado.idm.oclc.org/login?url=http://link.springer.com/10.1007/978-3-319-11280-0  |z Full Text (via Springer) 
880 8 |6 505-01/(S  |a Chapter 6: Immuno-Modulatory Role of Porins: Host Immune Responses, Signaling Mechanisms and Vaccine PotentialIntroduction; Role of Porins in Modulation of Immune Responses; Innate Immune Responses; Adaptive Immune Response; Signaling Cascades Initiated by Porins; Porins as Vaccine Candidates; Conclusion; References; Chapter 7: Vibrio cholerae Cytolysin: Structure-Function Mechanism of an Atypical β-Barrel Pore-Forming Toxin; Introduction; Vibrio cholerae Cytolysin; Structural Features of VCC; Structural Features of the VCC β-Barrel Pore; Mechanism of Membrane Pore Formation; Conclusion. 
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