Biochemical roles of eukaryotic cell surface macromolecules / Abhijit Chakrabarti.
Consists of critical reviews and original research papers from the 2014 International Symposium on the "Biochemical Role of Eukaryotic Cell Surface Macromolecules". Topics covered include: · neurochemical and biochemical analysis of cell surface glycoconjugates · membrane skeletal organiza...
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Format: | eBook |
Language: | English |
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Cham, Switzerland :
Springer,
2015.
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Series: | Advances in experimental medicine and biology ;
842. |
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MARC
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100 | 1 | |a Chakrabarti, Abhijit, |e author. | |
245 | 1 | 0 | |a Biochemical roles of eukaryotic cell surface macromolecules / |c Abhijit Chakrabarti. |
264 | 1 | |a Cham, Switzerland : |b Springer, |c 2015. | |
264 | 4 | |c ©2015. | |
300 | |a 1 online resource (407 pages) : |b illustrations (some color), tables. | ||
336 | |a text |b txt |2 rdacontent. | ||
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490 | 1 | |a Advances in Experimental Medicine and Biology, |x 2214-8019 ; |v Volume 842. | |
504 | |a Includes bibliographical references and index. | ||
505 | 0 | |6 880-01 |a Preface; Contents; Chapter 1: Human-Specific Evolutionary Changes in the Biology of Siglecs; Introduction; Human-Specific Changes in Siglecs; Siglec-1/Sialoadhesin; Siglec-3/CD33; Siglec-5 and -14; Siglec-6; Siglec-9; Siglec-11 and -16; Siglec-XII; Siglec-13; Siglec-17; Conclusions and Perspectives; References; Chapter 2: Structural Changes of GPI Anchor After Its Attachment to Proteins: Functional Significance; Introduction; Biosynthesis of GPI and Its Attachment to Proteins; GPI Remodeling Reactions That Occur After Attachment to Proteins; Inositol-Deacylation by PGAP1 in the ER. | |
505 | 8 | |a Removal of an EtNP Side Branch from the Second Mannose by PGAP5 in the ER Fatty Acid Remodeling of GPI-AP in the Golgi; Biological Significance of Fatty Acid Remodeling; References; Chapter 3: Novel Insights in Membrane Biology Utilizing Fluorescence Recovery After Photobleaching; The Dynamic Membrane; Fluorescence Recovery After Photobleaching; Lipid Dynamics by FRAP; GPCR Activation: Manifestations in Receptor Dynamics; Dynamic Confinement of GPCRs Upon Cholesterol Depletion: Insight from Bleach Area-Dependent FRAP; Are Signaling and Dynamics Correlated? | |
505 | 8 | |a Lateral Dynamics as Readout of Infection Conclusion and Future Perspectives; References; Chapter 4: Defects in Erythrocyte Membrane Skeletal Architecture; Introduction; Membrane Skeleton; Erythroid Membrane Skeleton; Lipid Bilayer: Membrane Skeleton Interactions; Assembly of the Membrane-Skeleton of Erythroid Cells; Defects in Membrane Skeleton; Hereditary Spherocytosis; Molecular Defects in HS; Pathophysiology; Laboratory Features and Treatment; Hereditary Elliptocytosis; Molecular Defects in HE; Laboratory Features and Treatment; Malaria and the Erythrocyte Membrane Skeleton Alterations. | |
505 | 8 | |a ConclusionReferences; Chapter 5: Membrane Rafts in the Erythrocyte Membrane: A Novel Role of MPP1p55; Introduction; Erythrocyte Membrane Rafts; Stomatin, Flotillins and MPP1 Are the Stable Components of Erythrocyte Rafts; Stomatin; Flotillins; MPP1; Visualization of Erythrocyte Membrane Rafts; Role of Erythrocyte Membrane Rafts in Signaling; Erythrocyte Rafts and Pathology; MPP1 and Its Palmitoylation Play a Crucial Role in Lateral Membrane Organization in Erythroid Cells; The Involvement of Actin in Erythrocyte Membrane Rafts Organization?; Conclusions; References. | |
520 | |a Consists of critical reviews and original research papers from the 2014 International Symposium on the "Biochemical Role of Eukaryotic Cell Surface Macromolecules". Topics covered include: · neurochemical and biochemical analysis of cell surface glycoconjugates · membrane skeletal organization · GPCRs and other receptors · biophysical approaches to study membrane interactions · glycoconjugate metabolism · dysregulation · molecular mechanisms involved in cell-cell and cell-matrix interaction · glycans in infectious and neurological diseases · cancer and glycosyltransferases as drug targets. | ||
588 | 0 | |a Print version record. | |
650 | 0 | |a Eukaryotic cells. | |
650 | 0 | |a Molecular biology. | |
650 | 0 | |a Cell receptors. | |
650 | 7 | |a Cell receptors. |2 fast |0 (OCoLC)fst00850227. | |
650 | 7 | |a Eukaryotic cells. |2 fast |0 (OCoLC)fst00916456. | |
650 | 7 | |a Molecular biology. |2 fast |0 (OCoLC)fst01024734. | |
776 | 0 | 8 | |i Print version: |a Chakrabarti, Abhijit. |t Biochemical roles of eukaryotic cell surface macromolecules. |d Cham, Switzerland : Springer, ©2015 |h ix, 411 pages |k Advances in experimental medicine and biology ; Volume 842 |x 2214-8019 |z 9783319112794 |w (DLC) 2014955053. |
830 | 0 | |a Advances in experimental medicine and biology ; |v 842. | |
856 | 4 | 0 | |u https://colorado.idm.oclc.org/login?url=http://link.springer.com/10.1007/978-3-319-11280-0 |z Full Text (via Springer) |
880 | 8 | |6 505-01/(S |a Chapter 6: Immuno-Modulatory Role of Porins: Host Immune Responses, Signaling Mechanisms and Vaccine PotentialIntroduction; Role of Porins in Modulation of Immune Responses; Innate Immune Responses; Adaptive Immune Response; Signaling Cascades Initiated by Porins; Porins as Vaccine Candidates; Conclusion; References; Chapter 7: Vibrio cholerae Cytolysin: Structure-Function Mechanism of an Atypical β-Barrel Pore-Forming Toxin; Introduction; Vibrio cholerae Cytolysin; Structural Features of VCC; Structural Features of the VCC β-Barrel Pore; Mechanism of Membrane Pore Formation; Conclusion. | |
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