Ibuprofen [electronic resource] : pharmacology, therapeutics and side effects / K.D. Rainsford.
Ibuprofen is one of the most successful drugs used worldwide for the treatment of mild to moderate pain and various inflammatory conditions, even in a low-dose form for over-the-counter (OTC), non-prescription sale. Over the past 40 years, ibuprofen has been proven to be as safe or safer and just as...
Saved in:
| Online Access: |
Full Text (via Springer) |
|---|---|
| Main Author: | |
| Format: | Electronic eBook |
| Language: | English |
| Published: |
Basel ; New York :
Springer,
©2012.
|
| Subjects: |
MARC
| LEADER | 00000cam a2200000xa 4500 | ||
|---|---|---|---|
| 001 | b7329165 | ||
| 006 | m o d | ||
| 007 | cr ||||||||||| | ||
| 008 | 130208s2012 sz ob 001 0 eng d | ||
| 005 | 20240418144329.3 | ||
| 019 | |a 829751567 |a 837185835 | ||
| 020 | |a 9783034804967 |q (electronic bk.) | ||
| 020 | |a 3034804962 |q (electronic bk.) | ||
| 020 | |z 3034804954 | ||
| 020 | |z 9781299337336 | ||
| 020 | |z 1299337333 | ||
| 020 | |z 9783034804950 | ||
| 035 | |a (OCoLC)spr827003729 | ||
| 035 | |a (OCoLC)827003729 |z (OCoLC)829751567 |z (OCoLC)837185835 | ||
| 037 | |a spr10.1007/978-3-0348-0496-7 | ||
| 040 | |a GW5XE |b eng |e pn |c GW5XE |d YDXCP |d COO |d OHS |d ZMC |d CDX |d OCLCO |d N$T |d E7B |d NUI |d NLGGC |d MHW |d OCLCQ | ||
| 049 | |a GWRE | ||
| 050 | 4 | |a RM666.I17 |b R35 2012 | |
| 100 | 1 | |a Rainsford, K. D., |d 1941- |0 http://id.loc.gov/authorities/names/n79111017 |1 http://isni.org/isni/000000008091913X. | |
| 245 | 1 | 0 | |a Ibuprofen |h [electronic resource] : |b pharmacology, therapeutics and side effects / |c K.D. Rainsford. |
| 260 | |a Basel ; |a New York : |b Springer, |c ©2012. | ||
| 300 | |a 1 online resource. | ||
| 336 | |a text |b txt |2 rdacontent. | ||
| 337 | |a computer |b c |2 rdamedia. | ||
| 338 | |a online resource |b cr |2 rdacarrier. | ||
| 505 | 0 | 0 | |g Introduction -- |t Biodisposition in Relation to Actions -- |t Mechanisms of Inflammation and Sites of Action of NSAIDs -- |t Clinical Efficacy -- |t Drug Derivatives and Formulations -- |t General Safety Profile -- |t Gastro-Intestinal Toxicity -- |t Cardiovascular Safety -- |t Renal Toxicity -- |t Hepatic Toxicity -- |t Other Adverse Reactions -- |t Global Assessment of Adverse Reactions and Human Toxicology -- |t Overall Assessment -- |g Summary. |
| 504 | |a Includes bibliographical references and index. | ||
| 520 | |a Ibuprofen is one of the most successful drugs used worldwide for the treatment of mild to moderate pain and various inflammatory conditions, even in a low-dose form for over-the-counter (OTC), non-prescription sale. Over the past 40 years, ibuprofen has been proven to be as safe or safer and just as effective as established non-steroidal anti-inflammatory drugs (NSAIDs) or coxibs. This book reviews the pharmacology, clinical uses and adverse effects of ibuprofen. Its disposition and unique modes of action in relation to clinical effects are discussed as well as various formulations and the impact of food and other variables on its actions and gastro-intestinal safety. The use of combinations of ibuprofen with other drugs (e.g. paracetamol, codeine and caffeine) are critically assessed. There are already some indications of potential therapeutic benefits of the drug combinations in treating certain painful conditions, while still retaining the relative safety benefits of ibuprofen (at least at OTC dosages). The impact of natural products and Chinese Medicines on the safety of ibuprofen is also reviewed. The book is written in a more general style, including explanatory diagrams, for anyone interested in the properties, actions and uses of ibuprofen. | ||
| 650 | 0 | |a Ibuprofen. |0 http://id.loc.gov/authorities/subjects/sh97005926. | |
| 650 | 0 | |a Ibuprofen |x Side effects. | |
| 776 | 0 | 8 | |i Print version: |z 9781299337336. |
| 856 | 4 | 0 | |u https://colorado.idm.oclc.org/login?url=http://link.springer.com/10.1007/978-3-0348-0496-7 |z Full Text (via Springer) |
| 907 | |a .b73291651 |b 03-24-21 |c 02-26-13 | ||
| 998 | |a web |b 05-01-17 |c g |d b |e - |f eng |g sz |h 0 |i 1 | ||
| 907 | |a .b73291651 |b 07-02-19 |c 02-26-13 | ||
| 944 | |a MARS - RDA ENRICHED | ||
| 907 | |a .b73291651 |b 05-23-17 |c 02-26-13 | ||
| 915 | |a I | ||
| 956 | |a Springer e-books | ||
| 956 | |b Springer Nature - Springer Biomedical and Life Sciences eBooks 2012 English International | ||
| 956 | |b Springer Nature - Springer Biomedical and Life Sciences eBooks 2012 English International | ||
| 999 | f | f | |i f343821f-9885-5b52-9d07-430a6cd47b5c |s d88b5bb5-e10b-5fa3-8a5a-f72bb13d9797 |
| 952 | f | f | |p Can circulate |a University of Colorado Boulder |b Online |c Online |d Online |e RM666.I17 R35 2012 |h Library of Congress classification |i Ebooks, Prospector |n 1 |