TRITOX [electronic resource] : a multiple parameter evaluation of tritium toxicity.
The increased use of nuclear reactors for power generation will lead to the introduction of tritium into the environment. The need for assessing possible immediate and long-term effects of exposure to this tritium led to the development of a broad program directed towards evaluating the possible som...
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Online Access |
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| Corporate Author: | |
| Format: | Government Document Electronic eBook |
| Language: | English |
| Published: |
Upton, N.Y. : Oak Ridge, Tenn. :
Brookhaven National Laboratory ; distributed by the Office of Scientific and Technical Information, U.S. Dept. of Energy,
1982.
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| Subjects: |
MARC
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| 035 | |a (TOE)5130620 | ||
| 040 | |a TOE |c TOE | ||
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| 086 | 0 | |a E 1.99:bnl-31581 | |
| 086 | 0 | |a E 1.99: conf-820736-1 | |
| 245 | 0 | 0 | |a TRITOX |h [electronic resource] : |b a multiple parameter evaluation of tritium toxicity. |
| 260 | |a Upton, N.Y. : |b Brookhaven National Laboratory ; |a Oak Ridge, Tenn. : |b distributed by the Office of Scientific and Technical Information, U.S. Dept. of Energy, |c 1982. | ||
| 300 | |a Pages: 36 : |b digital, PDF file. | ||
| 336 | |a text |b txt |2 rdacontent. | ||
| 337 | |a computer |b c |2 rdamedia. | ||
| 338 | |a online resource |b cr |2 rdacarrier. | ||
| 500 | |a Published through the Information Bridge: DOE Scientific and Technical Information. | ||
| 500 | |a 01/01/1982. | ||
| 500 | |a "bnl-31581" | ||
| 500 | |a " conf-820736-1" | ||
| 500 | |a "DE82018100" | ||
| 500 | |a 17. annual European Society for Radiation Biology meeting on effects of prenatal irradiation, Bordeaux, France, 26 Jul 1982. | ||
| 500 | |a Carsten, A.L. | ||
| 520 | 3 | |a The increased use of nuclear reactors for power generation will lead to the introduction of tritium into the environment. The need for assessing possible immediate and long-term effects of exposure to this tritium led to the development of a broad program directed towards evaluating the possible somatic and genetic effects of continuous exposure to tritiated water (HTO). Among the parameters measured are the genetic, cytogenetic, reproductive efficiency, growth, nonspecific lifetime shortening, bone marrow cellularity and stem cell content, relative biological effectiveness as compared to ¹³⁷Cesium gamma exposure, and related biochemical and microdosimetric evaluations. These parameters have been evaluated on animals maintained on HTO at 10 to 100 times the maximum permissible concentration (0.03 - 3.0 ..mu..Ci/ml) for HTO. Dominant lethal mutations, chromosome aberrations in regenerating liver, increased sister chromatid exchanges in bone marrow and reduction in bone marrow stem cell content have been observed at the higher concentrations. The relative biological effectiveness for HTO ingestion as compared to external ¹³⁷Cesium gamma exposures has been found to be between 1 and 2. | |
| 536 | |b AC02-76CH00016. | ||
| 650 | 7 | |a Beta Decay Radioisotopes. |2 local. | |
| 650 | 7 | |a Sister Chromatid Exchanges. |2 local. | |
| 650 | 7 | |a Stem Cells. |2 local. | |
| 650 | 7 | |a Cesium 137. |2 local. | |
| 650 | 7 | |a Biological Radiation Effects. |2 local. | |
| 650 | 7 | |a Electromagnetic Radiation. |2 local. | |
| 650 | 7 | |a Isotopes. |2 local. | |
| 650 | 7 | |a Tritium. |2 local. | |
| 650 | 7 | |a Internal Irradiation. |2 local. | |
| 650 | 7 | |a Computer Codes. |2 local. | |
| 650 | 7 | |a Tritium Compounds. |2 local. | |
| 650 | 7 | |a Bone Marrow Cells. |2 local. | |
| 650 | 7 | |a Ionizing Radiations. |2 local. | |
| 650 | 7 | |a Tritium Oxides. |2 local. | |
| 650 | 7 | |a Irradiation. |2 local. | |
| 650 | 7 | |a Animal Cells. |2 local. | |
| 650 | 7 | |a Life Span. |2 local. | |
| 650 | 7 | |a Chronic Exposure. |2 local. | |
| 650 | 7 | |a Connective Tissue Cells. |2 local. | |
| 650 | 7 | |a Reproduction. |2 local. | |
| 650 | 7 | |a Hydrogen Isotopes. |2 local. | |
| 650 | 7 | |a Early Radiation Effects. |2 local. | |
| 650 | 7 | |a Toxicity. |2 local. | |
| 650 | 7 | |a Animal Growth. |2 local. | |
| 650 | 7 | |a Rbe. |2 local. | |
| 650 | 7 | |a Radioisotopes. |2 local. | |
| 650 | 7 | |a Labelled Compounds. |2 local. | |
| 650 | 7 | |a Cell Proliferation. |2 local. | |
| 650 | 7 | |a Genetic Effects. |2 local. | |
| 650 | 7 | |a Mathematical Models. |2 local. | |
| 650 | 7 | |a Beta-minus Decay Radioisotopes. |2 local. | |
| 650 | 7 | |a Somatic Cells. |2 local. | |
| 650 | 7 | |a Radiation Effects. |2 local. | |
| 650 | 7 | |a Oxygen Compounds. |2 local. | |
| 650 | 7 | |a Gamma Radiation. |2 local. | |
| 650 | 7 | |a Mutations. |2 local. | |
| 650 | 7 | |a Biological Effects. |2 local. | |
| 650 | 7 | |a Odd-even Nuclei. |2 local. | |
| 650 | 7 | |a Alkali Metal Isotopes. |2 local. | |
| 650 | 7 | |a Cesium Isotopes. |2 local. | |
| 650 | 7 | |a Chromosomal Aberrations. |2 local. | |
| 650 | 7 | |a Chronic Irradiation. |2 local. | |
| 650 | 7 | |a Radiations. |2 local. | |
| 650 | 7 | |a T Codes. |2 local. | |
| 650 | 7 | |a Growth. |2 local. | |
| 650 | 7 | |a Genetic Radiation Effects. |2 local. | |
| 650 | 7 | |a Oxides. |2 local. | |
| 650 | 7 | |a Light Nuclei. |2 local. | |
| 650 | 7 | |a Delayed Radiation Effects. |2 local. | |
| 650 | 7 | |a Nuclei. |2 local. | |
| 650 | 7 | |a Years Living Radioisotopes. |2 local. | |
| 650 | 7 | |a Chalcogenides. |2 local. | |
| 650 | 7 | |a Radiation, Thermal, And Other Environ. Pollutant Effects On Living Orgs. And Biol. Mat.. |2 edbsc. | |
| 710 | 2 | |a Brookhaven National Laboratory. |4 res. | |
| 710 | 1 | |a United States. |b Department of Energy. |b Office of Scientific and Technical Information. |4 dst. | |
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