Whole-body autoradiographic microimaging [electronic resource] : Applications in radiopharmaceutical and drug research.

The whole-body autoradiographic (WBARG) microimaging technique is used for evaluation of the temporo-spatial distribution of radiolabeled molecules in intact animals as well as to determine the sites of accumulation of parent compounds and their metabolites. This technique is also very useful to det...

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Bibliographic Details
Online Access: Online Access
Corporate Author: Brookhaven National Laboratory (Researcher)
Format: Government Document Electronic eBook
Language:English
Published: Washington, D.C. : Oak Ridge, Tenn. : United States. Dept. of Defense ; distributed by the Office of Scientific and Technical Information, U.S. Dept. of Energy, 1991.
Subjects:

MARC

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500 |a Som, P.; Sacker, D.F. 
520 3 |a The whole-body autoradiographic (WBARG) microimaging technique is used for evaluation of the temporo-spatial distribution of radiolabeled molecules in intact animals as well as to determine the sites of accumulation of parent compounds and their metabolites. This technique is also very useful to determine the metabolism of a compound, toxicity, and effects of therapeutic interventions on the distribution of a compound in the whole body, by studying animals at different time intervals after injection of the radiolabeled compound. This report discusses various aspects of WBARG. 
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