Antiepileptic drugs and pregnancy : a guide for prescribers / MJ Eadie, FJE Vajda.
A description of our current understanding of antiepileptic drug use during pregnancy, this book includes chapters on the impact of seizures on the mother and developing child, changes in maternal physiology during pregnancy and its impact on drug disposition, and the pharmacokinetic differences bet...
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| Format: | eBook |
| Language: | English |
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Adis,
[2015]
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Table of Contents:
- Preface; Contents; Chapter 1: Introduction; References; Chapter 2: Antiepileptic Drugs and Becoming Pregnant; Achieving Pregnancy; The Situation in the Male; The Situation in the Female; Avoiding Pregnancy; References; Part I: Antiepileptic Drug Pharmacokinetics in Pregnancy; Chapter 3: Antiepileptic Drug Disposition in Pregnancy; Body Changes During Pregnancy; Changes in Physiology; Changes in Biochemistry; Lactation; Drug Disposition in Pregnancy and Lactation; Drug Absorption; Drug Distribution; Drug Elimination; Excretion of Unmetabolised Drug; Drug Metabolism; References.
- Chapter 4: The Older Antiepileptic DrugsPhenobarbitone; Chemistry; Pharmacodynamics; Pharmacokinetics; Absorption; Distribution; Elimination; Excretion Unchanged; Metabolism; Clinical Pharmacokinetics; Interactions; Adverse Effects; Teratogenicity; Pregnancy; The Mother; The Foetus; Breast Milk ; The Neonate; Phenytoin; Chemistry; Pharmacodynamics; Pharmacokinetics; Absorption; Distribution; Elimination; Excretion Unchanged; Metabolism; Clinical Pharmacokinetics; Interactions; Interactions Altering Phenytoin Concentrations; Phenytoin Affecting Other Substances.
- Adverse EffectsNervous System; Skin and Gums; Bone; Lymphoid Tissue; Folates; Cardiovascular Effects; Other Effects; Teratogenicity; Pregnancy; The Mother; The Foetus; Breast Milk ; The Neonate; Carbamazepine; Chemistry; Pharmacodynamics; Pharmacokinetics; Absorption; Distribution; Elimination; Excretion Unchanged; Metabolism; Clinical Pharmacokinetics; Interactions; Adverse Effects; Teratogenesis; Pregnancy; The Mother; The Foetus; Breast Milk ; The Neonate; Valproate; Chemistry; Pharmacodynamics; Pharmacokinetics; Absorption; Distribution; Elimination.
- Excretion UnchangedMetabolism; Clinical Pharmacokinetics; Interactions; Adverse Effects; Teratogenicity; Pregnancy; The Mother; The Foetus; Breast Milk ; The Neonate; References; Chapter 5: Commonly Used Newer Antiepileptic Drugs; Lamotrigine; Chemistry; Pharmacodynamics; Pharmacokinetics; Absorption; Distribution; Elimination; Excretion Unchanged; Metabolism; Clinical Pharmacokinetics; Interactions; Adverse Effects; Teratogenesis; Pregnancy; The Mother; The Foetus; Breast Milk ; The Neonate; Topiramate; Chemistry; Pharmacodynamics; Pharmacokinetics; Absorption.
- Distribution Elimination; Excretion Unchanged; Metabolism; Clinical Pharmacokinetics; Interactions; Adverse Effects; Teratogenicity; Pregnancy; The Mother; The Foetus; Breast Milk ; The Neonate; Levetiracetam; Chemistry; Pharmacodynamics; Pharmacokinetics; Absorption; Distribution; Elimination; Excretion Unchanged; Metabolism; Clinical Pharmacokinetics; Interactions; Adverse Effects; Teratogenicity; Pregnancy; The Mother; The Foetus; Breast Milk ; The Neonate; References; Chapter 6: Antiepileptic Drugs Sometimes Used in Pregnancy; Oxcarbazepine; Chemistry.