Antiepileptic drugs and pregnancy : a guide for prescribers / MJ Eadie, FJE Vajda.
A description of our current understanding of antiepileptic drug use during pregnancy, this book includes chapters on the impact of seizures on the mother and developing child, changes in maternal physiology during pregnancy and its impact on drug disposition, and the pharmacokinetic differences bet...
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Full Text (via ProQuest) |
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| Format: | eBook |
| Language: | English |
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Cham :
Adis,
[2015]
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MARC
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| 100 | 1 | |a Eadie, Mervyn J., |e author. | |
| 245 | 1 | 0 | |a Antiepileptic drugs and pregnancy : |b a guide for prescribers / |c MJ Eadie, FJE Vajda. |
| 264 | 1 | |a Cham : |b Adis, |c [2015] | |
| 264 | 4 | |c ©2016. | |
| 300 | |a 1 online resource (xii, 232 pages) : |b color illustrations. | ||
| 336 | |a text |b txt |2 rdacontent. | ||
| 337 | |a computer |b c |2 rdamedia. | ||
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| 504 | |a Includes bibliographical references and index. | ||
| 505 | 0 | |a Preface; Contents; Chapter 1: Introduction; References; Chapter 2: Antiepileptic Drugs and Becoming Pregnant; Achieving Pregnancy; The Situation in the Male; The Situation in the Female; Avoiding Pregnancy; References; Part I: Antiepileptic Drug Pharmacokinetics in Pregnancy; Chapter 3: Antiepileptic Drug Disposition in Pregnancy; Body Changes During Pregnancy; Changes in Physiology; Changes in Biochemistry; Lactation; Drug Disposition in Pregnancy and Lactation; Drug Absorption; Drug Distribution; Drug Elimination; Excretion of Unmetabolised Drug; Drug Metabolism; References. | |
| 505 | 8 | |a Chapter 4: The Older Antiepileptic DrugsPhenobarbitone; Chemistry; Pharmacodynamics; Pharmacokinetics; Absorption; Distribution; Elimination; Excretion Unchanged; Metabolism; Clinical Pharmacokinetics; Interactions; Adverse Effects; Teratogenicity; Pregnancy; The Mother; The Foetus; Breast Milk ; The Neonate; Phenytoin; Chemistry; Pharmacodynamics; Pharmacokinetics; Absorption; Distribution; Elimination; Excretion Unchanged; Metabolism; Clinical Pharmacokinetics; Interactions; Interactions Altering Phenytoin Concentrations; Phenytoin Affecting Other Substances. | |
| 505 | 8 | |a Adverse EffectsNervous System; Skin and Gums; Bone; Lymphoid Tissue; Folates; Cardiovascular Effects; Other Effects; Teratogenicity; Pregnancy; The Mother; The Foetus; Breast Milk ; The Neonate; Carbamazepine; Chemistry; Pharmacodynamics; Pharmacokinetics; Absorption; Distribution; Elimination; Excretion Unchanged; Metabolism; Clinical Pharmacokinetics; Interactions; Adverse Effects; Teratogenesis; Pregnancy; The Mother; The Foetus; Breast Milk ; The Neonate; Valproate; Chemistry; Pharmacodynamics; Pharmacokinetics; Absorption; Distribution; Elimination. | |
| 505 | 8 | |a Excretion UnchangedMetabolism; Clinical Pharmacokinetics; Interactions; Adverse Effects; Teratogenicity; Pregnancy; The Mother; The Foetus; Breast Milk ; The Neonate; References; Chapter 5: Commonly Used Newer Antiepileptic Drugs; Lamotrigine; Chemistry; Pharmacodynamics; Pharmacokinetics; Absorption; Distribution; Elimination; Excretion Unchanged; Metabolism; Clinical Pharmacokinetics; Interactions; Adverse Effects; Teratogenesis; Pregnancy; The Mother; The Foetus; Breast Milk ; The Neonate; Topiramate; Chemistry; Pharmacodynamics; Pharmacokinetics; Absorption. | |
| 505 | 8 | |a Distribution Elimination; Excretion Unchanged; Metabolism; Clinical Pharmacokinetics; Interactions; Adverse Effects; Teratogenicity; Pregnancy; The Mother; The Foetus; Breast Milk ; The Neonate; Levetiracetam; Chemistry; Pharmacodynamics; Pharmacokinetics; Absorption; Distribution; Elimination; Excretion Unchanged; Metabolism; Clinical Pharmacokinetics; Interactions; Adverse Effects; Teratogenicity; Pregnancy; The Mother; The Foetus; Breast Milk ; The Neonate; References; Chapter 6: Antiepileptic Drugs Sometimes Used in Pregnancy; Oxcarbazepine; Chemistry. | |
| 520 | 3 | |a A description of our current understanding of antiepileptic drug use during pregnancy, this book includes chapters on the impact of seizures on the mother and developing child, changes in maternal physiology during pregnancy and its impact on drug disposition, and the pharmacokinetic differences between the various anti-seizure medications. It also deals with the possible harmful effects of antiepileptic drug exposure during pregnancy on the physical and intellectual development of the fetus. Clinicians have to balance the potential adverse effects of the medicine for the fetus and mother-to-be against the risks that uncontrolled seizures hold for both when treating pregnant women with antiepileptic drugs. Only recently have enough scientific data emerged to provide a rational basis for treatment decisions that take in both aspects. This work provides a single, accessible, and up-to-date resource for busy clinicians. | |
| 588 | 0 | |a Online resource; title from PDF title page (SpringerLink, viewed September 2, 2015) | |
| 650 | 0 | |a Anticonvulsants. | |
| 650 | 0 | |a Obstetrical pharmacology. | |
| 650 | 0 | |a Epilepsy in pregnancy. | |
| 650 | 0 | |a Pregnancy |x Complications. | |
| 650 | 0 | |a Pregnancy. | |
| 650 | 7 | |a Pregnancy |x Complications. |2 fast |0 (OCoLC)fst01075106. | |
| 650 | 7 | |a Pregnancy. |2 fast |0 (OCoLC)fst01075102. | |
| 650 | 7 | |a Anticonvulsants. |2 fast |0 (OCoLC)fst00810472. | |
| 650 | 7 | |a Epilepsy in pregnancy. |2 fast |0 (OCoLC)fst00914215. | |
| 650 | 7 | |a Obstetrical pharmacology. |2 fast |0 (OCoLC)fst01042986. | |
| 700 | 1 | |a Vajda, F. J. E. |q (Frank J. E.), |e author. | |
| 776 | 0 | 8 | |i Print version: |a Eadie, MJ. |t Antiepileptic Drugs and Pregnancy : A Guide for Prescribers. |d Cham : Springer International Publishing, ©2015 |z 9783319214337. |
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