Principles of CNS Drug Development : From Test Tube to Patient / John Kelly.
This title acts as a primer, giving students and newcomers to the field an opportunity to learn about the breadth of the CNS drug discovery and the various stages in the drug discovery process-from evaluating drugs for their efficacy and safety in animals and humans to identifying future drug target...
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Full Text (via Wiley) |
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| Format: | eBook |
| Language: | English |
| Published: |
Chichester, West Sussex ; Hoboken, NJ :
J. Wiley,
2009.
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Table of Contents:
- Principles of CNS drug development; Contents; Acknowledgements; Preface; Abbreviations; 1 Introduction; 2 An overview of the major CNS disorders; 3 Neurobiological substrates of CNS disorders; 4 Current pharmacological targets; 5 Premarketing efficacy evaluation; 6 Pharmacokinetic considerations: Absorption, distribution, metabolism and elimination; 7 Safety concerns; 8 Preclinical and clinical safety evaluation; 9 CNS drug targets in development and future perspectives; Appendices; Index.