Principles of CNS Drug Development : From Test Tube to Patient / John Kelly.
This title acts as a primer, giving students and newcomers to the field an opportunity to learn about the breadth of the CNS drug discovery and the various stages in the drug discovery process-from evaluating drugs for their efficacy and safety in animals and humans to identifying future drug target...
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Full Text (via Wiley) |
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| Main Author: | |
| Format: | eBook |
| Language: | English |
| Published: |
Chichester, West Sussex ; Hoboken, NJ :
J. Wiley,
2009.
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| Subjects: |
MARC
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| 100 | 1 | |a Kelly, John, |d 1961- | |
| 245 | 1 | 0 | |a Principles of CNS Drug Development : |b From Test Tube to Patient / |c John Kelly. |
| 260 | |a Chichester, West Sussex ; |a Hoboken, NJ : |b J. Wiley, |c 2009. | ||
| 300 | |a 1 online resource (xx, 304 pages) : |b illustrations. | ||
| 336 | |a text |b txt |2 rdacontent. | ||
| 337 | |a computer |b c |2 rdamedia. | ||
| 338 | |a online resource |b cr |2 rdacarrier. | ||
| 347 | |a data file |2 rda. | ||
| 504 | |a Includes bibliographical references and index. | ||
| 505 | 0 | |a Principles of CNS drug development; Contents; Acknowledgements; Preface; Abbreviations; 1 Introduction; 2 An overview of the major CNS disorders; 3 Neurobiological substrates of CNS disorders; 4 Current pharmacological targets; 5 Premarketing efficacy evaluation; 6 Pharmacokinetic considerations: Absorption, distribution, metabolism and elimination; 7 Safety concerns; 8 Preclinical and clinical safety evaluation; 9 CNS drug targets in development and future perspectives; Appendices; Index. | |
| 520 | |a This title acts as a primer, giving students and newcomers to the field an opportunity to learn about the breadth of the CNS drug discovery and the various stages in the drug discovery process-from evaluating drugs for their efficacy and safety in animals and humans to identifying future drug targets. The content of the book is heavily informed by recent experimental evidence and the impediments in the pipeline of drug discovery. It draws on the attempts to develop translational research strategies in CNS drug development. The title highlights the emergence of a "critical path" for the develop. | ||
| 546 | |a English. | ||
| 588 | 0 | |a Print version record. | |
| 650 | 0 | |a Neuropharmacology. | |
| 650 | 0 | |a Drug development. | |
| 650 | 7 | |a Drug development. |2 fast |0 (OCoLC)fst00898670. | |
| 650 | 7 | |a Neuropharmacology. |2 fast |0 (OCoLC)fst01036458. | |
| 776 | 0 | 8 | |i Print version: |a Kelly, John, 1961- |t Principles of CNS drug development. |d Chichester, West Sussex ; Hoboken, NJ : J. Wiley, 2009 |w (DLC) 2009041400. |
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