ALDH1A1 Deficiency in Gorlin Syndrome Suggests a Central Role for Retinoic Acid and ATM Deficits in Radiation Carcinogenesis [electronic resource]

We hypothesize that aldehyde dehydrogenase 1A1 (ALDH1A1) deficiency will result in impaired ataxia-telangiectasia mutated (ATM) activation in a retinoic acid-sensitive fashion. Data supporting this hypothesis include (1) reduced ATM activation in irradiated primary dermal fibroblasts from ALDH1A1-de...

Full description

Saved in:
Bibliographic Details
Online Access: Full Text (via OSTI)
Corporate Author: Pacific Northwest National Laboratory (U.S.) (Researcher)
Format: Electronic eBook
Language:English
Published: Washington, D.C. : Oak Ridge, Tenn. : United States. Department of Energy. Office of Science ; Distributed by the Office of Scientific and Technical Information, U.S. Department of Energy, 2014.
Subjects:

Internet

Full Text (via OSTI)

Online

Holdings details from Online
Available