Drug repositioning : approaches and applications for neurotherapeutics / [edited by] Joel Dudley and Laura Berliocchi.

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Bibliographic Details
Online Access: Full Text (via Taylor & Francis)
Other Authors: Dudley, Joel T., Berliocchi, Laura
Format: eBook
Language:English
Published: Boca Raton : CRC Press, [2017]
Series:Frontiers in neurotherapeutics series.
Subjects:
Table of Contents:
  • Chapter 1 Scientific and Commercial Value of Drug Repurposing / David Cavalla
  • chapter 2 Repurposing for Alzheimer's and Parkinson's Diseases
  • The Ideas, the Pipeline, the Successes, and the Disappointments / Hermann Mucke
  • chapter 3 Contribution of Not-for-Profit Organizations to Drug Repurposing / Bruce Bloom
  • section I The Rationale and Economics of Drug Repositioning
  • chapter 4 Systematic Drug Repositioning / Spyros N. Deftereos Aris Persidis Andreas Persidis Eftychia Lekka Christos Andronis Vassilis Virvillis
  • chapter 5 Technical Tools for Computational Drug Repositioning / Francesco Napolitano
  • chapter 6 RNAi Screening toward Therapeutic Drug Repurposing / Nichole Orr-Burks Byoung-Shik Shim Olivia Perwitasari Ralph A. Tripp
  • chapter 7 Phenotypic Screening / Christine M. Macolino-Kane John R. Ciallella Christopher A. Lipinski Andrew G. Reaume
  • section II Repositioning Approaches and Technologies From Serendipity to Systematic and Rational Strategies
  • chapter 8 A Case Study
  • Chlorpromazine / Francisco López-Muñoz Cecilio Álamo Silvia E. García-Ramos
  • chapter 9 Drug Repurposing for Central Nervous System Disorders
  • A Pillar of New Drug Discovery / Mondher Toumi Aleksandra Caban Anna Kapuśniak Szymon Jarosławski Cecile Rémuzat
  • chapter 10 Repurposing Opportunities for Parkinson's Disease Therapies / Giulia Ambrosi Silvia Cerri Fabio Blandini
  • chapter 11 Drug Candidates for Repositioning in Alzheimer's Disease / Maria P. del Castillo-Frias Andrew J. Doig
  • chapter 12 Promising Candidates for Drug Repurposing in Huntington's Disease / Francesca Romana Fusco Emanuela Paldino
  • chapter 13 Drug Repositioning Opportunities in Psychiatry / Alexander W. Charney Joseph R. Scarpa Douglas M. Ruderfer Dennis S. Charney
  • chapter 14 Pharmacology of Amyotrophic Lateral Sclerosis
  • Old Strategies and New Perspectives / Tiziana Petrozziello Valentina Tedeschi Alba Esposito Agnese Secondo
  • chapter 15 Repositioning Clinic-Ready Compounds for the Treatment of Spinal Muscular Atrophy / Faraz Farooq
  • chapter 16 Rescuing Ischemic Brain Injury by Targeting the Immune Response through Repositioned Drugs / Diana Amantea Giacinto Bagetta
  • section III Drug Repositioning for Nervous System Diseases.