Handbook of drug screening [electronic resource] / edited by Ramakrishna Seethala, Litao Zhang.
Building upon the foundation of basics discussed in the previous edition, the Second Edition provides a more in-depth look at the latest methods and technologies of advanced drug screening, an essential function of drug discovery.
Saved in:
| Online Access: |
Full Text (via Taylor & Francis) |
|---|---|
| Other Authors: | , |
| Format: | Electronic eBook |
| Language: | English |
| Published: |
New York :
Informa Healthcare,
©2009.
|
| Edition: | 2nd ed. |
| Series: | Drugs and the pharmaceutical sciences ;
v. 196. |
| Subjects: |
Table of Contents:
- Key factors for successful high-throughput screening / John G. Houston
- Critical components in high-throughput screening : challenges and new trends / Litao Zhang, Martyn N. Banks, and John G. Houston
- Hit-to-probe-to-lead optimization strategies : a biology perspective to conquer the valley of death / Anuradha Roy [and others]
- Signal detection platforms for screening in drug discovery / Ramakrishna Seethala
- Proteomic analysis in drug discovery / Haiteng Deng, Yang Xu, and Linqi Zhang
- Screening and characterization of g-protein-coupled receptor ligands for drug discovery / Ge Zhang and Mary Ellen Cvijic.
- Nuclear hormone receptor screening in drug discovery / Ramakrishna Seethala and Litao Zhang
- Emerging novel high-throughput screening technologies for cell-based assays / ILona Kariv [and others]
- In vitro strategies for ion channel screening in drug discovery / Ravikumar Peri, Mark Bowlby, and John Dunlop
- Wheat from chaff : general and mechanistic triage of screening hits for enzyme targets / Mark R. Harpel
- Protein kinases and phosphatases / Pirthipal Singh
- MicroRNA strategies in drug discovery / Wishva B. Herath
- Strategies for screening of biologic therapeutics / Ian Foltz and Francesca Civoli.
- Cryopreserved cells in functional cell-based HTS assays / Geetha Shankar and Kirk McMillan
- High-content screening with a special emphasis on cytotoxicity and cell health measurements Ralph J. Garippa and Ann F. Hoffman
- Effective application of drug metabolism and pharmacokinetics in drug discovery Sharon Diamond and Swanny Yeleswaram
- Compound management for drug discovery : an overview Moneesh Chatterjee and Martyn N. Banks
- Practical approach to quantitative high throughput screening Wei Zheng, Ke Liu, and James Inglese
- Enabling the large-scale analysis of quantitative high-throughput screening data Noel T. Southall [and others]
- Application of nanobiotechnologies for drug discovery / K.K. Jain.