In vivo MR techniques in drug discovery and development [electronic resource] / edited by Nicolau Beckmann.
Imaging technologies are receiving much attention in the pharmaceutical industry because of their potential for accelerating drug discovery and development. Magnetic Resonance (MR) Imaging is one of the principal modalities since it allows anatomical, functional, metabolic, and to a certain extent e...
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Format: | Electronic eBook |
Language: | English |
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New York :
Taylor & Francis,
2006.
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Table of Contents:
- Ch 1. The drug discovery and development process : a brief overview / Alex Matter
- ch 2. The drug discovery and development process : opportunities and challenges for MR techniques / Nicolau Beckmann and Markus Rudin
- Editorial comments
- ch 3. Imaging as biomarker for decision-making in drug development / Richard Hargreaves and John A. Wagner
- Editorial comments
- ch 4. Design of contrast agents for molecular imaging in vivo / Silvio Aime, Giovanni B. Giovenzana, Dario Longo, and Enzo Terreno
- Editorial comments
- ch 5. Rapid phenotyping of mice with MRI / X. Josette Chen and R. Mark Henkelman
- Editorial comments
- ch 6. Magnetic resonance imaging and spectroscopy in transgenic mice modeling Alzheimer's disease / Thomas Mueggler
- ch 7. Imaging Alzheimer's disease with MRI / Scott A. Small
- ch 8. MRI and MRS in animal models of focal cerebral ischemia / Markus Rudin, Peter R. Allegrini, and Martin Rausch
- ch 9. MRI in clinical studies of stroke / Eric Juettler, Jochen B. Fiebach, and Peter D. Schellinger
- Editorial comments
- ch 10. Pharmacologic magnetic resonance imaging (phMRI) / Bruce G. Jenkins, Ji-Kyung Choi, Joseph B. Mandeville, and Yin-Ching Iris Chen
- ch 11. Brain fMRI in clinical pharmacological studies / Irene Tracey, Petra Schweinhardt, and Chas Bountra
- ch 12. Imaging inflammatory processes of the brain : multiple sclerosis as an example / Martin Rausch, Iris-Katharina Penner, Cedric Berger, and Markus Rudin
- Editorial comments
- ch 13. Functional and molecular magnetic resonance imaging of preclinical cancer models in drug discovery and development / Zaver M. Bhujwalla, Kristine Glunde, Ellen Ackerstaff, Arvind P. Pathak, Barjor Gimi, Noriko Mori, Venu Raman, and Dmitri Artemov
- ch 14. MR for clinical pharmacological studies in cancer / Geoffrey S. Payne, David J. Collins, Elizabeth M. Charles-Edwards, Mounia Beloueche-Babari, and Martin O. Leach
- ch 15. Molecular imaging in cancer therapies of the future / Chrit Moonen.