Handbook of assay development in drug discovery [electronic resource] / edited by Lisa K. Minor.

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Bibliographic Details
Online Access: Full Text (via Taylor & Francis)
Other Authors: Minor, Lisa
Format: Electronic eBook
Language:English
Published: Boca Raton : CRC/Taylor & Francis, ©2006.
Series:Drug discovery series ; 5.
Subjects:

MARC

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245 0 0 |a Handbook of assay development in drug discovery  |h [electronic resource] /  |c edited by Lisa K. Minor. 
260 |a Boca Raton :  |b CRC/Taylor & Francis,  |c ©2006. 
300 |a 1 online resource (464 pages) :  |b illustrations (some color) 
336 |a text  |b txt  |2 rdacontent. 
337 |a computer  |b c  |2 rdamedia. 
338 |a online resource  |b cr  |2 rdacarrier. 
490 1 |a Drug discovery series ;  |v 5. 
504 |a Includes bibliographical references and index. 
505 0 |a Protein Kinases in Drug Discovery: Rationale, Success, and Challenge; Dana L. Johnson and Jan L. Sechler ; An Introduction to the Protein Tyrosine Phosphatase Gene Family and Screening Assay Development; Dominique Perrin and Rob Hooft van Huijsduijnen ; Time-Resolved Fluorescence Based Assays for Kinases; Zhuyin Li and Tina Garyantes ; Development of High-throughput Screening Assays in Scintillating Microplates (FlashPlates) to Identify Inhibitors of Kinase Activity; Stewart Emanual ; Development of High-Throughput Screening Assays for Kinase Drug Targets using AlphaScreen™ Technology; D. Wenham, C. Illy, J.A. St. Pierre, and N. Bouchard ; Homogeneous High-Throughput Screening (HTS) Assays for Serine/Threonine Kinases Using ß-Galactosidase Enzyme Fragment Complementation; I. Vainshtein, T. Naqvi, A. Lim, R. Rouhani, L. Kauffman, R. Singh, and R.M. Eglen ; IMAP Assays for Assaying Protein Kinases; R. 
505 0 |a Sportsman ; A Homogenous, Luminescent, High-Throughput, Versatile Assay for a Wide Range of Kinases; S.A. Goueli, K. Hsiao, and B. Bulleit ; Proteases as Drug Targets; R.L. Thurmond and J.P. Edwards ; A Comparison of Homogeneous Bioluminescent and Fluorescent Methods for Protease Assays; M. O'Brien ; Scintillation Proximity Assay (SPA) Receptor Binding Assays; J.R. Cook, R. Graves, K. Lowitz, M.J. Price-Jones, J.A. Berry and K.T. Hughes ; Radioligand Binding Filtration Assay: Full Automation; S.K.F. Wong ; Nuclear Receptors As Drug Targets; P.D. Pelton ; Nuclear Receptor Scintillation Proximity Assays; D. Powell and M.J. Price-Jones ; Homogenous Assay Development for Nuclear Receptor Using the AlphaScreen Technology; N. Rouleau and R. Boss é; Development of Nuclear Receptor Homogenous Assay Using the Lance Technology; N. Rouleau, P. Hurskainen, I. Hemmil ä and R. 
505 0 |a Boss é; The Emerging Role of Cell-based Assays in Discovery; R. Garippa ; The Preparation of Cells for High-Content Screening; A. Hoffman ; The Evolution of cAMP Assays; P. Kasila and H. Harney ; A Homogenous Fluorescent Polariaiton assay for Inositol 1, 4, 5-Trisphoshpate (Ins P3 ); P. Fung, R. Singh, L. Kauffman, R.M. Eglen and T. Naqvi ; Scintillation Proximity Assay of Inositol Phosphates; W. Zheng and P. Brandish ; Measuring Calcium Mobilization with Gq -Coupled GPCRs Using the Fluorometric Imaging Plate Reader (FLIPR); J. Dunlop, Y. Zhang, R. Ring and D. Kowal ; Development of FLIPR-Based HTS Assay for Gi -Coupled GPCRs; C. Chen, C. Smith, L. Minor, and B. 
505 0 |a Damiano ; Aurora Assays; P, Kunapuli ; Membrane Potential Based Assays for Ion Channels and Electrogenic Transporters; Q, Lü, S, Lin, and J, Dunlop ; Reporter Gene Assays for Drug Discovery; K.A. Houck, W.P. Bocchinfuso, M.S. Dowless, and K.M. Borchert ; mRNA Detection from Cells Using Quantigene® Branched DNA Technology; L. Minor ; Homogeneous Miltiwell Assays for Measuring Cell Viability, Cytotoxicity and Apoptosis; Terry Riss, R.A. Moravec, M.A. O'Brien, E.M. Hawkins, and A. Niles ; Development of Image-Bases Assays for Drug Discovery; S.M. Catalano ; GPCR Internalization Measured by Image Analysis; R. Graves, M.J. Francis, L. Smith, J.R. Cook, and E.J. Adie ; TRANSFLUOR®, a Universal Cell-Based Assay for Screening G-Protein Coupled Receptors; R. Oakley C.L. Cowan, C.C. Hudson, and C.R. Loomis. 
588 0 |a Print version record. 
650 0 |a Drug development  |v Handbooks, manuals, etc. 
650 0 |a Drugs  |x Research  |v Handbooks, manuals, etc. 
650 0 |a Drugs  |x Design  |v Handbooks, manuals, etc. 
650 7 |a Drug development.  |2 fast  |0 (OCoLC)fst00898670. 
650 7 |a Drugs  |x Design.  |2 fast  |0 (OCoLC)fst00898790. 
650 7 |a Drugs  |x Research.  |2 fast  |0 (OCoLC)fst00898894. 
655 0 |a Electronic book. 
655 7 |a Handbooks and manuals.  |2 fast  |0 (OCoLC)fst01423877. 
700 1 |a Minor, Lisa.  |0 http://id.loc.gov/authorities/names/n2005056220  |1 http://isni.org/isni/0000000427662688. 
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830 0 |a Drug discovery series ;  |v 5.  |0 http://id.loc.gov/authorities/names/n2005049696. 
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