Competition and allostery govern substrate selectivity of cyclooxygenase-2 [electronic resource]

<p>Cyclooxygenase-2 (COX-2) oxygenates arachidonic acid (AA) and its ester analog, 2-arachidonoylglycerol (2-AG), to prostaglandins (PGs) and prostaglandin glyceryl esters (PG-Gs), respectively. While the efficiency of oxygenation of these substrates by COX-2 in vitro is similar, cellular bios...

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Online Access: Full Text (via OSTI)
Corporate Author: Oak Ridge National Laboratory (Researcher)
Format: Electronic eBook
Language:English
Published: Oak Ridge, Tenn. : Oak Ridge, Tenn. : Oak Ridge National Laboratory ; Distributed by the Office of Scientific and Technical Information, U.S. Department of Energy, 2015.
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