Competition and allostery govern substrate selectivity of cyclooxygenase-2 [electronic resource]
<p>Cyclooxygenase-2 (COX-2) oxygenates arachidonic acid (AA) and its ester analog, 2-arachidonoylglycerol (2-AG), to prostaglandins (PGs) and prostaglandin glyceryl esters (PG-Gs), respectively. While the efficiency of oxygenation of these substrates by COX-2 in vitro is similar, cellular bios...
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Format: | Electronic eBook |
Language: | English |
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Oak Ridge, Tenn. : Oak Ridge, Tenn. :
Oak Ridge National Laboratory ; Distributed by the Office of Scientific and Technical Information, U.S. Department of Energy,
2015.
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