Protein Lipidation / edited by Fuyuhiko Tamanoi and David S. Sigman.
This is the first compilation of protein lipidation enzymes. This volume summarizes recent dramatic developments regarding enzymes responsible for protein lipidation, a process critical for a number of physiological functions, including cell proliferation and morphology. Inhibitors of protein lipida...
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| Online Access: |
Full Text (via ScienceDirect) |
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| Other Authors: | , |
| Format: | eBook |
| Language: | English |
| Published: |
San Diego, CA :
Academic Press,
2001.
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| Edition: | Third edition. |
| Series: | Enzymes ;
v. 21. |
| Subjects: |
| Summary: | This is the first compilation of protein lipidation enzymes. This volume summarizes recent dramatic developments regarding enzymes responsible for protein lipidation, a process critical for a number of physiological functions, including cell proliferation and morphology. Inhibitors of protein lipidation have recently been shown to be useful as anticancer drugs. Enzymatic mechanisms, mutational analysis, and structural studies are presented. Key Features * The enzymatic mechanisms of protein lipidation * Three-dimensional structures of protein farnesytransferase, protein geranylgeranytransferase II, and n-myristoryltransferase. |
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| Physical Description: | 1 online resource (x, 322 pages) : illustrations, 14 pages of plates. |
| Bibliography: | Includes bibliographical references and index. |
| ISBN: | 9780121227227 0121227227 9780080542430 0080542433 |