Phosphodiesterase inhibitors [electronic resource] / edited by Christian Schudt, Gordon Dent and Klaus F. Rabe.

Non-selective inhibitors of cyclic nucleotide phosphodiesterase (PDE), such as theophylline, have been used extensively since 1958. In the decade of the '70s, various PDE isoenzymes were defined which led to the development of the second generation of PDE inhibitors. Currently a variety of thes...

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