Origin and evolution of biodiversity / Pierre Pontarotti editor.
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| Format: | eBook |
| Language: | English |
| Published: |
Cham, Switzerland :
Springer,
[2018]
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Table of Contents:
- Intro; Preface; Acknowledgements; Contents; Genome/Phenotype Evolution; Pmela and Tyrp1b Contribute to Melanophore Variation in Mexican Cavefish; 1 Introduction; 2 Materials and Methods; 2.1 Melanophore Scoring; 2.2 Quantitative Trait Locus (QTL) Association Mapping; 2.3 Gene Ontology (GO) Term Analysis; 2.4 RNA-Seq, Qualitative, and QPCR Expression Analyses; 2.5 Whole-Mount In Situ Hybridization; 2.6 Functional Validation in Zebrafish with MO Knockdowns; 3 Results.
- 3.1 Cavefish × Surface Fish Hybrid Individuals Demonstrate Diversity in Melanophore Numbers in Distinct Regions Spanning the Body3.2 QTL Analysis Revealed 19 Genomic Regions Associated with Complex Melanophore Variation; 3.3 Comparative Analyses Narrowed Melanophore QTL Positions to Critical Genomic Regions in Astyanax and Danio; 3.4 Tyrp1b and Pmela Are Two Candidate Genes Associated with Numerical Melanophore Diversity; 3.5 Tyrp1b and Pmela Demonstrate Distinct Melanophore-Specific Expression Patterns Between Cave and Surface Morphotypes.
- 3.6 Functional Analyses of Tyrp1b and Pmela Reveal Altered Melanophore Dispersion and Structure in Morphants4 Discussion; 4.1 Tyrp1b and Pmela Contribute to Melanophore Number Variation in Cavefish; 4.2 Analysis of Complex Pigmentation Informs the Genetic Basis for Regressive Evolution in Cavefish; 4.3 Astyanax mexicanus Enables Investigation of Degenerative Pigmentation Disorders; References; Adaptive Evolution of Yeast Under Heat Stress and Genetic Reconstruction to Generate Thermotolerant Yeast; 1 Introduction; 2 Heat Stress in S. cerevisiae.
- 3 Mechanisms of Thermotolerance in S. cerevisiae4 Methods for Improving Stress Tolerance; 5 Acquisition of Thermotolerance in Yeast by Adaptive Evolution; 6 Comprehensive Analysis of the Thermotolerant Yeast Strain YK60-1; 7 Genomic Analysis to Identify the Key Mutations for Improved Thermotolerance; 8 Conclusions and Perspectives; References; The Domestication Syndrome in Phaseolus Crop Plants: A Review of Two Key Domestication Traits; 1 Introduction; 2 Domestication Areas of Phaseolus Beans; 3 Phenotypic Evaluations of Two Key Domestication Traits in Phaseolus Beans; 3.1 Pod Shattering.
- 4 Seed Size5 Molecular Genetics and Genetic Architecture of Pod Shattering; 6 Genetic Architecture of Seed Weight; 7 Conclusions; References; Tracing the Evolutionary Origin of the Gut-Brain Axis; 1 Introduction-The Holobiont Imperative; 2 Developmental Symbiosis and the Evolution of New Organs; 3 Thoughts About the Evolution of the Nervous System; 4 Of Neurological Disorders and Animals as Complex Systems: Why Bacteria Matter; 5 The Gut-Brain Axis; 6 The Hydra Holobiont-A Model Organism to Study the Microbiota-Gut-Brain Axis; 7 Hydra Neurons Shape the Microbiota.